Intercurrent change at the pathology of esophagus disease, have one part and esophagus cancer form have particular concern, call the pathological change before cancer. Basically have: 　
(1) esophagus inflammation: Disease suffers from a lot of esophagus and stomach to often erupt simultaneously esophagitis disease. The area is sent high in esophagus cancer, esophagitis disease proportion is higher, and the incidence of a disease of epithelial hyperplasia and esophagus cancer becomes esophagitis disease, esophagus positive closes. 　
(2) esophagus is epithelial and proliferous: As a result of the long-term effect of all sorts of exciter, as a result causes esophagus epithelial hyperplasia and inflammation, epithelial finally happening canceration, this already was organized what investigation confirms pathology and the esophagus is epithelial and proliferous epidemiology that send an area high. To the epithelial research discovery other esophagus cancer, most case of illness has epithelial proliferation, have the malign development of different level further. 　
(3) esophagus ulcer: Esophagus ulcer and esophagus inflammation are OK each other is cause and effect. The disease before cancer suffers from often also may erupt simultaneously esophagus ulcer. Although esophagus ulcer does not see more, but the relationship with esophagus cancer is more close. The person that debaucjed of esophagus mucous membrane and shallow ulcer appear in inchoate esophagus cancer is not scarce. 　
(Blaze of 4) esophagus mucous membrane: Prep above of intercurrent in esophagus cancer blaze is normal person, explain esophagus cancer and esophagus blaze have particular concern, but be not very close. At present the importance of blaze of esophagus mucous membrane still does not have unanimous view. 　
(5) esophagus scar is narrow: Ulcer, chronic inflammation, chemistry is burnable wait to all can cause esophagus scar stricture, but research is more is alkali kind burnable the relation of the esophagus scar stricture that cause and esophagus cancer. The canceration rate that somebody thinks esophagus is narrow is 1000 times higher than average person. 　

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