Li Haigang Su Qiaozhu (Sun Yixian of Zhongshan medical university commemorates hospital Guangzhou 510120) )
Keyword: Chinese traditional medicine wither of tumor cancer cell dies function of cancerous gene immunity
Cellular wither dies, call cellular program sex death again (PCD) , it is a kind of when organize cleared and certain cell normally distinctive cellular death mode, it also appears below a variety of pathology condition. Cellular wither dies the hyperplasia that controlling organism cell and become divided, the happening of tumor and grow the effect with wait for all respects to rising main. The growth with normal organism is existing in development process cellular wither dies, radiation, tumour changes cure agent, heat, purify or increase hormone, fight antigen of Apo-1 antibody, Fas and cell the explicit element such as poisonous lymphocyte also but revulsive cell wither dies. In recent years, the cellular wither with revulsive Chinese traditional medicine dies to cause the attention of scientific research worker increasingly, the article emphasizes revulsive to Chinese traditional medicine cell wither to die reach its the mechanism makes the likelihood be summed up.
The tumor cell wither with 1 revulsive Chinese traditional medicine dies
A variety of malignant tumor cells of the mankind lost wither of unripe to certain and exciting hair cell to die the ability of reaction. This kind of phenomenon is most outstanding in organization of move sex tumour. Visible, tumor is the disease with cellular hyperplasia and unusual become divided not only, also be cellular wither dies unusual disease. Strengthen wither of cell of revulsive to medicaments tumour to die the research that reachs its mechanism, the precaution that undoubted meeting gives tumor and cure offer new thinking and way. Chinese traditional medicine treats tumor not only poisonous side effect is little, and effect way is more extensive, the active ingredient of single ingredient Chinese traditional medicine and preparation of medicine made of two or more ingredients die in wither of revulsive tumour cell in having main effect.
Chinese traditional medicine of 1.1 single ingredient the influence that active ingredient dies to cellular wither
Consider to discover in great quantities, chinese traditional medicine active ingredient (or monomer) wither of cell of can revulsive tumour dies. Bu Shizhong choose the monomer composition SSD that extracts from inside the root of Chinese thorowax, observe the inhibition that SSD grows to the cell into the law with mix into of 3H- thymus pyrimidine, DNA gel electrophoresis and wither of cell of analysis of art of cell drifting type die. Result discovery, after classics SSD action, person acute is early the mix into of 3H- thymus pyrimidine of HL-60 of cell of young bead leukaemia is entered rate is apparent reduce, show time and dosage to depend on a relation, sluggish of block of cell of analysis of appearance of cell drifting type at G1 period appear wither dies period, demonstrative SSD but wither of revulsive HL-60 cell dies. From Korea excessive sheep the Chinese traditional medicine that in leavessing of pulse plants, extracts glucoside of monomer excessive sheep leavessing of pulse plants (ICA) , the sweet Xi of extraction content Lan of the acid of active ingredient ursine fruit that extracts from inside asparagus and E art parts action at HL-60 cell, can revulsive its produce cellular wither to die. With MTT fast mensuration and analysis of appearance of cell drifting type consider to discover, the root of kudzu vine extracts content (PR) but occurrence wither of cell of SMMC-7721 of revulsive person liver cancer dies period. With Mao Bing the extraction content of 3 leaves Qi handles cell of P 388 of element of the P388 of cell of small rat leukaemia, mildew that fight A to reach fight agglutinin cell of enzymatic P 388 after 48 hours, in electrophoresis of gel of DNA agaragar candy, department of 3 kinds of cells all appears DNA of typical ladder shape ruptures, and for chroma dependence, demonstrative wool handle the extraction content of 3 leaves Qi but wither of cell of revulsive P 388 dies.
Previous12 Next

Previous:Laser is revulsive the research general situation that cellular wither dies
Next:no article